The Santa Fe Trail between Missouri and Santa Fe, in what was once Mexico, ran through the southeast corner of Colorado, and this stretch is now a Colorado State Scenic Byway as well as a National Scenic Byway. This reliable route was traversed by a bevy of historic figures, including frontiersman Kit Carson, explorer John C. Fremont, adventuring women like Julia Archibald Holmes, Hispanic businessman Don Felipe Chavez, and American traders William and Charles Bent. Today, you can explore the path once taken by these trailblazers of the past.